Amblyopic patient adherence under patching treatment / Adesão de pacientes amblíopes sob uso de oclusores

ABSTRACT Objective: To evaluate the effectiveness of text messaging in improving adherence to occlusion therapy for amblyopia. The secondary objective was to correlate the responses given in a self-reporting questionnaire with treatment outcome (improvement in visual acuity). Methods: This is a prospective, randomized, blinded clinical trial. The patients' parents or legal guardians in the intervention group received text messages reminding them of the importance of patching. The control group received no text messages. At final evaluation, after a period of three to six months, the patients' parents or legal guardians answered a self-reporting questionnaire to evaluate adherence to treatment. Results: The study included 34 patients with an average age of 5.35 years, 20 in the intervention group and 14 in the control group. According to the results of the self-reporting questionnaire, 50% of the study population was considered as having low adherence to treatment, 29% as having medium adherence, and 21% as having good adherence. There was no significant difference between trial groups. The comparison between an improvement in visual acuity and the mean value obtained in the self-reporting questionnaire showed a significant association between this improvement and adherence to treatment (p=0.03). Conclusion: The present study did not find a correlation between text messaging and an improvement in adherence to occlusion therapy, as shown by previous studies for different treatments. A statistically significant association was identified between an improvement in visual acuity and a good therapeutic adherence, as measured by the self-reporting questionnaire. This finding allows us to recommend using a self-reporting questionnaire as a simple method to measure adherence to treatment and help decisions about therapeutic strategies to be adopted in the patient's continuing treatment.

RESUMO Objetivo: Avaliar a eficácia do envio de mensagens de texto na melhora da adesão ao tratamento oclusivo da ambliopia. O objetivo secundário foi correlacionar as respostas dadas no questionário autorreportado e os resultados obtidos no tratamento (melhora da acuidade visual). Métodos: Ensaio clínico prospectivo, mascarado e randomizado. Os pais ou responsáveis legais dos pacientes no grupo intervenção receberam mensagens de texto para lembrar a importância dos oclusores. O grupo controle não recebeu mensagens. Na avaliação geral após 3 a 6 meses, os responsáveis responderam a um questionário autorreportado para avaliar a aderência ao tratamento. Resultados: Foram incluídos 34 pacientes com idade média de 5,35 anos; 20 eram do grupo intervenção. A população do estudo foi considerada 50% pouco aderente ao tratamento, 29% com aderência média e 21% com boa aderência, de acordo com resultado do questionário autorreportado. Não houve diferença significativa entre os grupos estudados. Quando comparada a relação entre a melhora da acuidade visual com o valor médio do questionário autorreportado, foi observada associação significativa da melhora com a adesão ao tratamento (p=0,03). Conclusão: Este estudo não mostrou melhora da aderência ao tratamento oclusivo com o envio de mensagens de texto, como tinha sido observado em estudos anteriores para outros tratamentos. Foi identificada uma relação estatisticamente significativa entre a melhora na acuidade visual e boa aderência terapêutica medida pelo questionário autorreportado. Isso permite recomendar o uso do questionário autorreportado como uma forma simples de mensurar aderência ao tratamento e auxiliar nas decisões sobre estratégias a serem adotadas na continuidade do seguimento do paciente.

"Escolas" do jogo: investigações e aplicações na educação escolar, esporte e lazer - estudo 1 / Game "schools": investigations and applications in school education, sport and leisure - study 1

Este artigo objetiva apresentar uma revisão das produções acadêmicas de algumas correntes teórico-metodológicas, denominadas de "escolas", que abordam o jogo na Educação Física brasileira. Trata-se de uma pesquisa de abordagem qualitativa, de cunho descritivo, do tipo bibliográfico. Os critérios de inclusão para definir as "escolas" foram: tradição de pesquisas produzidas por mais de uma década, formação profissional em grupos de pesquisa com orientações na graduação e pós-graduação e com contribuições didáticas e investigativas utilizadas como referências na área. A análise de conteúdo das obras principais (livros) deu-se a partir das unidades temáticas: educação escolar, esporte e lazer. O estudo identificou quatro escolas, assim denominadas: Jogo, entre a rua e a escola; Jogo Tradicional; Praxiologia Motriz do jogo e Escola Brincante. Neste artigo, está abordado o conceito de jogo e as contribuições das produções bibliográficas para a educação escolar, para o esporte e para o lazer, das duas primeiras escolas.

This article aims to present a review of the academic productions of some theoretical-methodological currents, called "schools", which approach the game in Brazilian Physical Education. This is a qualitative, descriptive, bibliographic research. The inclusion criteria to define the "schools" were: tradition of the researches produced for more than a decade, professional training in research groups with guidance at undergraduate and postgraduate levels and with didactic and investigative contributions used as references in the area. The content analysis of the main works (books) was based on the thematic units: school education, sport and leisure. The study identified four schools, named as follows: Game, between the street and the school; Traditional Game; Game Driving Praxiology and Playing School. In this article, the concept of game and the contributions of bibliographic productions for school education, for sport and for leisure, from the first two schools are discussed.

Bacteriemia por Enterobacter cancerogenus en un paciente con trauma pélvico / Enterobacter cancerogenus bacteremia in a patient with pelvic trauma

Resumen Existen escasas comunicaciones de infecciones por Enterobacter cancerogenus. Aunque ha sido aislado en heridas contaminadas asociadas a traumas, también ha sido reportado como agente etiológico en una amplia variedad de otras infecciones, siendo infrecuente la presencia de bacteriemia. Presentamos el primer caso reportado en Chile de una bacteriemia causada por este microorganismo, en un varón de 28 años con una fractura de pelvis estable debido a un accidente de tránsito de alta energía. Tuvo una buena respuesta clínica al tratamiento con ertapenem.

Abstract There are few cases reports of Enterobacter cancerogenus infections. Although it has been isolated in contaminated wounds associated with trauma, it has also been reported as an etiological agent in a wide variety of other infections, with the presence of bacteremia being infrequent. We present the first case reported in Chile of a bacteremia caused by this agent, in a 28-year-old patient with a stable pelvic fracture due a high-energy traffic accident. He had a good clinical response to treatment with ertapenem.

Dosis de refuerzo de vacuna SARS CoV-2 para la prevención de COVID-19: Desafío en un escenario con incertezas / SARS CoV-2 booster dose for COVID-19 prevention: challenge in an uncertain scenario

Al 16 de julio pasado existían 108 vacunas en etapa clínica de desarrollo, 28 de ellas con estudios en fase III y 6 autorizadas por la Organización Mundial de la Salud (OMS) según datos publicados al 3 de junio (AstraZeneca/Oxford, Johnson and Johnson/Janssen, Moderna, Pfizer/BionTech, Sinopharm, Sinovac) (1,2). A la vez, las entidades regulatorias como la FDA (Food and Drugs Agency) y la EMA (European Medicine Agency) han autorizado para uso de emergencia las vacunas de los productores Pfizer/BioNTech, Moderna, AstraZeneca y Janssen (3) y en Chile el Instituto de Salud Pública ha autorizado 6 vacunas (Pfizer, CoronaVac, Astrazeneca, CanSino, Janssen, Sputnik). En las últimas semanas, en el contexto de la preocupante propagación de la variante Delta (B.1.617.2) del SARS-CoV-2, la compañía Pfizer solicitó a la FDA la autorización para la administración de una dosis de refuerzo (booster) con su vacuna BNT162b2 , luego de que el análisis interino de datos provenientes de la población vacunada en Israel mostrará una reducción significativa de los anticuerpos neutralizantes a los seis meses de completado el esquema primario, solicitud que generó debate en la comunidad científica. Hasta ahora los datos disponibles sobre eficacia de la vacuna BNT162b2 en escenario de circulación de variantes sugieren que continúa siendo altamente efectiva (4,5). Los estudios para definir la eventual necesidad de una dosis de refuerzo a diferentes esquemas primarios están en etapas de reclutamiento inicial en varios países.(AU)

Mamoplastia de aumento e mastopexia com retalho em cambalhota a partir de abdominoplastia reversa / Augmentation mammoplasty and mastopexy with somersault flap from reverse abdominoplasty

Introdução: As mamas e o abdômen passam por grandes modificações morfológicas com perdas ponderais maciças. A mamoplastia de aumento é um dos procedimentos mais realizados na cirurgia plástica, ao contrário da abdominoplastia reversa, pouco descrita. Porém, em pacientes com flacidez abdominal superior que desejam o aumento mamário, a mamoplastia de aumento por meio da abdominoplastia reversa (AMBRA) torna possível o aprimoramento das mamas e do contorno abdominal simultaneamente. O objetivo deste trabalho é descrever um caso de mamoplastia de aumento e mastopexia utilizando retalho em cambalhota a partir de abdominoplastia reversa. Relato de Caso: Paciente do sexo feminino, parda, com história de perda ponderal maciça e com mamoplastia redutora e abdominoplastia prévias, evoluiu com ptose mamária e lipodistrofia em abdômen superior. Foi submetida à abdominoplastia reversa com utilização do retalho dermogorduroso epigástrico para projeção da mama. A paciente apresentou boa evolução pós-operatória, com resultado cirúrgico satisfatório. Discussão: As perdas ponderais maciças podem resultar em deformidades nas mamas e no abdômen que exigem cirurgias reparadoras. A remodelação mamária é difícil e pode exigir a utilização de tecidos adjacentes. A abdominoplastia, por sua vez, é a técnica mais consagrada para o rejuvenescimento do tronco; entretanto, quando a flacidez atinge principalmente o abdômen superior, a abdominoplastia reversa torna-se uma opção. Em casos em que o desejo de mamoplastia de aumento se associa ao excesso de volume supraumbilical, deve-se considerar a AMBRA. A mamoplastia de aumento por meio da abdominoplastia reversa revelou ser uma técnica viável neste caso, com resultado final satisfatório.

Introduction: The breasts and abdomen undergo significant morphological changes with massive weight loss. Breast augmentation is one of the most commonly performed procedures in plastic surgery, unlike reverse abdominoplasty, which has been little described. However, in patients with upper abdominal flaccidity who want breast augmentation, breast augmentation through reverse abdominoplasty (AMBRA) makes it possible to improve the breasts and abdominal contour simultaneously. This work aims to describe a case of breast augmentation and mastopexy using a somersault flap from reverse abdominoplasty. Case Report: Female patient, brown, with a history of massive weight loss and previous mammoplasty and abdominoplasty, evolved with breast ptosis and lipodystrophy in the upper abdomen. She underwent reverse abdominoplasty using an epigastric dermofat flap for breast projection. The patient had a good postoperative evolution, with satisfactory surgical results. Discussion: Massive weight loss can result in deformities in the breasts and abdomen that require reparative surgery. Breast remodeling is arduous and may require the use of adjacent tissues. Abdominoplasty, in turn, is the most established technique for rejuvenating the trunk; however, when sagging mainly affects the upper abdomen, reverse abdominoplasty becomes an option. In cases where the desire for breast augmentation is associated with excess supraumbilical volume, AMBRA should be considered. Breast augmentation using reverse abdominoplasty proved to be a viable technique in this case, with a satisfactory final result.

Prevalence and associated factors in community-dwelling subjects - a population-based study

SUMMARY OBJECTIVES To assess the prevalence of nocturia and identify factors associated with it in a community-dwelling population. METHODS A cross-sectional study was conducted in subjects aged 45 years or more and registered with a Family Doctor Program. Information was collected about nocturia, other urinary symptoms, physical examination, co-morbidities, demographics, socio-economic, and lifestyle factors. Multiple logistics regression models were developed to analyze associated factors for nocturia according to gender and the number of nocturnal micturitions(≥1 and ≥2). RESULTS Out of the 661 individuals included in the study, 62.3% were women. Among the women, the prevalence rates for nocturia ≥1 time and ≥2 times were, respectively, 68.4% and 49%, whereas, among the men, they were 64.3% and 43.8%. Among the women, nocturia ≥1 time was associated with brown skin, a higher BMI, lower schooling, and calcium channel blockers(CCB) use, while nocturia ≥2 times showed association with higher BMI, lower schooling, obstructive sleep apnea (OSA), and the use of CCB. Among the men, nocturia ≥1 time was associated positively with age, alcohol intake, and OSA, and negatively with angiotensin receptor blockers and beta-blockers use. Besides, nocturia ≥2 times was associated with age, not having health insurance, and OSA. CONCLUSIONS Nocturia is a condition highly prevalent in the studied population. For the female subjects, a higher BMI, lower schooling, and the use of CCB were associated with nocturia regardless of the definition used, whereas, among the men, that same association was found with age, not having health insurance, and OSA.

RESUMO OBJETIVOS Estimar a prevalência de noctúria e identificar fatores demográficos, socioeconômicos, clínicos e de estilo de vida associados ao sintoma em uma população comunitária. MÉTODO Estudo transversal em indivíduos com 45 anos ou mais. Foram obtidas informações demográficas, socioeconômicas, sobre noctúria, outros sintomas urinários, exame físico, comorbidades e estilo de vida. As análises foram feitas separadamente de acordo com o gênero e com o número de micções noturnas (≥1 vez e ≥2 vezes). RESULTADOS Dentre os 661 indivíduos incluídos, 62,3% eram mulheres. Entre elas, a prevalência de noctúria ≥1 vez e ≥2 vezes foi, respectivamente, de 68,4% e 49%, enquanto entre os homens foi de 64,3% e 43,8%. Entre as mulheres, a noctúria ≥1 mostrou associação com cor da pele parda, maior IMC, baixa escolaridade e uso de bloqueadores dos canais de cálcio (BCC), enquanto noctúria ≥2 vezes mostrou associação com maior IMC, baixa escolaridade, apneia obstrutiva do sono (AOS) e uso de BCC. Entre os homens, a noctúria ≥1 vez esteve associada positivamente com idade, ingestão de álcool e AOS, e negativamente com uso de bloqueadores dos receptores da angiotensina e de beta-bloqueadores. Além disso, noctúria ≥2 vezes associou-se a idade, não ter plano de saúde e AOS. CONCLUSÕES A noctúria é uma condição altamente prevalente na população estudada. Para as mulheres, IMC elevado, baixa escolaridade e uso de BCC estiveram associados com noctúria independente da definição, enquanto que, para os homens, a mesma associação foi identificada com idade, não ter plano de saúde e AOS.

Impacto en el consumo de amikacina y ceftriaxone en una unidad de emergencias de adultos, luego de la implementación de una guía para el tratamiento de la infección urinaria alta / Impact on the consumption of ceftriaxone and amikacin in an adult emergency unit, after the implementation of a guide for the treatment of pyelonephritis

Introducción: los programas de optimización del uso de antimicrobianos son fundamentales para mejorar los resultados clínicos de los pacientes. Objetivos: determinar el impacto en el consumo de amikacina y ceftriaxona, además de cambios de sensibilidad de las principales bacterias en la unidad de emergencias del hospital Carlos van Buren de Valparaíso, Chile, luego de la implementación de una guía para el tratamiento de la ITU alta. Materiales y método: estudio cuasi-experimental antes/después. Se implementó una guía de tratamiento para la ITU alta, la cual fue enviada vía WhatsApp a los médicos de la unidad. Luego se midieron las dosis diarias definidas (DDD) de amikacina y ceftriaxona y se compararon con las DDD de los mismos meses del año anterior. Además se extrajo la sensibilidad de E.coli, K. pneumonia y P.mirabilis aisladas de urocultivos. Resultados: posterior a la intervención hubo un aumento de las DDD de amikacina y una disminución de las de ceftriaxona. K.pneumoniae mantuvo su sensibilidad a amikacina y la aumentó para cefotaxima, ertapenem y meropenem. Conclusiones: la implementación de una guía de tratamiento de la ITU alta aumentó el consumo de amikacina y disminuyó el de ceftriaxona. K.pneumoniae aumentó su sensibilidad a cefotaxima, ertapenem y meropenem.

Introduction: different antimicrobial stewardship programs are fundamental to improve clinical results in patients. Objectives: to determine the impact on amikacin and ceftriaxone consumption, in addition to knowing changes in sensitivity of the main agents in the emergency unit of the Carlos van Buren Hospital in Valparaíso, Chile, after the implementation of a treatment guide for pyelonephritis. Materials and methods: quasi-experimental before/after study. A treatment guide was implemented for pyelonephritis. The guide was sent by WhatsApp to all clinicians in the emergency unit. Following the intervention, amikacin and ceftriaxone defined daily dose (DDD) were measured and compared with the DDD for the same months of the previous year. In addition, the sensitivity of E.coli, K. pneumonia and P.mirabilis isolated from urine cultures was extracted. Results: after the intervention there was a sustained increase of the DDD of amikacin and a decrease in the DDD of ceftriaxone in the months studied period. K. pneumoniae maintained its sensitivity to amikacin and increased it to cefotaxime, ertapenem, and meropenem. Conclusions: The guide's implementation for treatment of high UTI in the emergency unit of the Carlos van Buren hospital increased the consumption of amikacin and decreased that of ceftriaxone. K. pneumoniae increased its sensitivity to cefotaxime, ertapenem and meropenem.

A herbal oil in water nano-emulsion prepared through an ecofriendly approach affects two tropical disease vectors

ABSTRACT Lippia alba (Mill.) N.E.Br. ex Britton & P. Wilson, Verbenaceae, is considered a great source of a bioactive volatile oil. Due to the wide range of known chemotypes, its chemical analysis is very important. Among the several activities of this volatile oil, a potential larvicidal action against Culicidae species is highlighted. However, the low water miscibility of volatile oils limits their application in aqueous media. Oil in water nano-emulsions are in the spotlight of novelty to solve this main problem. Thus, the aim of the present study was to obtain this nanostructured system with L. alba volatile oil (citral chemotype) and evaluate its larvicidal activity against Aedes aegypti and Culex quinquefasciatus larvae. The major compounds were geranial (30.02%) and neral (25.26%). Low mean droplet size (117.0 ± 1.0 nm) and low polydispersity index (0.231 ± 0.004) were observed and no major changes were observed after seven days of storage. LC50 values against C. quinquefasciatus and A. aegypti third-instar larvae were respectively 38.22 and 31.02 ppm, while LC90 values were, respectively, 59.42 and 47.19 ppm. The present study makes use of a low energy, solvent-free and ecofriendly method with reduced costs. Thus, this paper contributes significantly to phyto-nanobiotechnology of larvicidal agents, opening perspectives for the utilization of L. alba volatile oil in integrated practices of vector control.

Los Hongos en la salud y la enfermedad. Parte I. / Fungi in health and disease. Part I.

Los hongos son organismos eucariontes que tienen nutrición absortiva, con presencia en los más variados ambientes y sustratos. Han sido parte de la historia del hombre y su desarrollo, siendo útiles tanto en la alimentación como en la medicina, producción de enzimas, actividad industrial y silvicultura. Sin embargo, también tienen la capacidad de producir infecciones superficiales y profundas en humanos y animales, contaminar e infectar granos, frutas, plantas y generar verdaderos desastres ecológicos.

Fungi are eukaryotic organisms, its nutrition is absorptive and they are widespread present in environment and substrates. They have been part of the history of human being and his development: they are useful as food, in medicine, enzyme production, in the industrial activity and forestry. However they have the capacity of infect superficial and deep human and animal tissues, contaminate and infect grains, fruits, plants and even produce environmental disasters.

Diagnosis of health care actions: a territorial analysis from the user's perspective / Diagnóstico de ações de saúde: uma análise territorial sob a perspectiva do usuário

ABSTRACT Objective: to describe the development of community health actions from the user's perspective. Methods: a descriptive study carried out in a small city in the south of Brazil, in 2017, with 639 literate residents of both genders. The sample was calculated in a weighted system by neighborhoods, streets and age group, and data were collected by 25 community health workers, distributed into 6 Basic Health Units (UBS). The research instrument included questions about the existence and the awareness of the user about community health education activities. Data were analyzed using the Statistical Package for Social Sciences (SPSS) software version 22.0. Results: 76.3% of the participants identified frequent community health actions; of these, 67.3% had a nurse present and 70%, a community health workers. 63.6% of the participants thought these actions stimulate the population to reflect on their health and illness, 62.5% self-care, 66% health protection measures and 56.4%, believed that these actions influence behavioral changes. Conclusion: from the perspective of the user, the activities developed fulfilled their expectations about community actions related to health promotion; the results also show that the participants are aware of the actions developed in the city and their significant effectiveness for habits changes. However, the data demonstrate centralized activities that require a re-signification of practices through permanent education on health promotion.

RESUMO Objetivo: descrever o desenvolvimento de ações comunitárias de saúde sob a ótica do usuário. Métodos: estudo descritivo realizado em um munícipio de pequeno porte no sul do Brasil em 2017, com 639 residentes, de ambos os sexos e alfabetizados. A amostra foi calculada de forma ponderada por bairros, ruas e faixa etária, e a coleta de dados realizada por 25 agentes comunitárias, distribuídas nas 6 Unidades Básicas de Saúde (UBS). O instrumento de pesquisa abrangeu questões concernentes a existência e conhecimento do usuário sobre atividades comunitárias de educação em saúde. Os dados foram analisados através do software Statistical Package for the Social Sciences (SPSS) versão 22,0. Resultados: 76,3% identificam realização de ações comunitárias frequentes em relação à saúde; destas, 67,3% com atuação do enfermeiro e 70% dos agentes comunitários de saúde; acerca das ações, 63,6% afirmam que elas estimulam o sujeito a refletir sobre sua condição de saúde e doença, 62,5% sobre autocuidado, 66% medidas de proteção à saúde e 56,4% acreditam que essas ações influenciam a mudança de comportamento das pessoas. Conclusão: na perspectiva dos usuários, as atividades desenvolvidas atendem sua expectativa sobre ações comunitárias relacionadas à promoção da saúde; também demonstram ter conhecimento da realização destas ações desenvolvidas no município com abrangência significativa sobre a efetividade das ações para mudanças de hábitos. No entanto, os dados demonstram atividades centralizadas que necessitam de uma ressignificação da prática por meio de educação continuada sobre promoção da saúde.

Nanosuspension of quercetin: preparation, characterization and effects against Aedes aegypti larvae

Abstract Aedes aegypti (Diptera: Culicidae) is the main vector of some neglected diseases, including dengue. It is very important to develop formulations that increase effectiveness of vector control with low toxicity. Quercetin is a plant-derived flavonoid that modulates the development of some insects. The low water solubility of quercetin impairs the development of water-dispersible commercial products. To circumvent this problem, the preparation of nanoformulations is considered promising. Thus, this study aimed to evaluate the effect of bulk and quercetin nanosuspension against A. aegypti larvae and also to investigate their ecotoxicity. Quercetin nanosuspension was produced by a solvent displacement method followed by solvent evaporation and was maintained in two different temperatures (4 and 25 ºC). Its size distribution and zeta potential were monitored along 30 days. The influence of quercetin nanosuspension and bulk-quercetin was investigated at various concentrations against A. aegypti and the green algae Chlorella vulgaris. The quercetin nanosuspension presented higher stability at 4 ºC and negative zeta potential values. Quercetin nanosuspension and bulk-quercetin adversely affected the larvae development, especially at the highest concentrations. Larvae mortality was between 44% and 100% (48 h) for quercetin nanosuspension at 100 and 500 ppm, respectively. The bulk-quercetin induced around 50% mortality regardless the concentration used at this same time-period. Absence of emerging mosquitoes from water was observed on the survival larvae of all the treated groups. Quercetin nanosuspension was less toxic than bulk-quercetin against C. vulgaris, especially at higher concentrations. These data indicate that quercetin nanosuspension may represent a potential larvicide for A. aegypti control, once they induced larvae death and inhibited the survival ones to emerge from water. In addition, it did not demonstrated ecotoxicity against a non-target organism, highlighting its better properties, when compared to the bulk-quercetin.

Mapa dos jogos tradicionais infantis no município de Conde-PB / Map of traditional games for children in the municipality of Conde-PB

Esta pesquisa objetivou construir um mapa dos jogos mais praticados por crianças e adolescentes no município de Conde-PB e analisar as relações que os praticantes realizam com os espaços públicos e com os materiais utilizados nas brincadeiras. Trata-se de uma pesquisa descritiva, de abordagem qualitativa. Foram realizadas observações nas comunidades de Barra de Gramame, Capim-açu, Caxitu, Garapu, Guaxinduba, Gurugi, Mata da Chica, Mituaçu, Paripe, Pituaçu, Pousada de Conde, Salsa e Utinga. Estas comunidades foram escolhidas devido o acesso as suas localidades, apesar de todas possuírem características rurais semelhantes e estradas de difícil tráfego. Em cada uma das localidades foram feitas duas visitas, cada uma com duração de duas horas, totalizando 52 horas de observações. Foram observados 33 jogos vividos nos mais diferentes espaços: rios, ruas, terrenos, dentre outros espaços. O estudo demonstrou como a diversidade da cultura lúdica infantil ressignifi ca os espaços públicos em espaços de lazer. Foi observado que os terrenos, ruas e rios possuem signifi cados para as crianças porque são continuamente transformados em espaços de socialização. Assim também os materiais que são reutilizados para realizar jogos, a exemplo das cordas, no cabo de guerra e dos papelões nas brincadeiras de casinha. A partir dos resultados encontrados foi construído um mapa, em que se destaca a relação das características rurais do entorno com a produção de jogos pelas crianças, como parte do cotidiano cultural. Estes jogos mapeados se apresentam como propriedade da cultura lúdica local e constituinte do patrimônio cultural universal que é repassado e atualizado de geração a geração, em diferentes comunidades....(AU)

This research aimed to build a map of the most practiced games by children and adolescents in the municipality of Conde-PB and also to analyze the relations that they perform at public spaces and what are the used materials in the games. For that, we used a descriptive-qualitative approach. Observations were made in the communities of Barra de Gramame, Capim-açu, Caxitu, Garapu, Guaxinduba, Gurugi, Mata da Chica, Mituaçu, Paripe, Pituaçu, Pousada de Conde, Salsa and Utinga. These communities were chosen due to the access to their localities, although they all have similar rural characteristics and diffi cult traffi c routes. In each of the locations we madeira two visits, each lasting two hours, totaling 52 hours of observations. There were 33 games played in the most diff erent spaces: rivers, streets, terrains, among other spaces. The study demonstrated how the diversity of children's recreational culture re-signifi espublic spaces in leisure spaces. It was observed that land, streets and rivers have meanings for children because they are continually transformed into spaces of socialization. As well as the materials that are reused to make games, like ropes, turn into the tug of war and the cardboard into house plays. From the results found, a map was constructed, highlighting the relation between the rural characteristics of the environment and the production of games by the children, as part of the cultural daily life. These mapped games are presented as the property of the local play culture and constituent of the universal cultural heritage that passes on to generations and updated from diff erent communities....(AU)

Frecuencia de Epidermophyton floccosum en dermatofitos aislados en un laboratorio de la Región de Valparaíso, Chile. Período 1980-2010 / Frequency of Epidermophyton floccosum in isolated dermatophytea laboratory from the Region of Valparaiso, Chile. Time frame: 1990-2010

Resumen Introducción: Las dermatofitosis son infecciones comunes en humanos, provocadas por hongos de los géneros Trichophyton, Microsporum y Epidermophyton. Objetivo: Determinar la frecuencia de E. floccosum en dermatofitos aislados en un laboratorio de la Región de Valparaíso durante las últimas tres décadas. Conocer las localizaciones más frecuentes, los grupos etarios y sexo de los pacientes afectados por este agente. Materiales y Método: Se revisaron los informes de cultivos superficiales con desarrollo de E. floccosum, Microsporum spp y Trichophyton spp de las tres últimas décadas del laboratorio de Micología de la Universidad de Valparaíso. Se registró en una planilla Excel el resultado del cultivo, edad, sexo y ubicación de la lesión de los pacientes. Resultados: El total de dermatofitosis con agente identificado fue de 6.780. En 26 casos hubo desarrollo de E. floccosum, de éstos, 73% (19/26) fueron en hombres y con una edad promedio de 37 años. La frecuencia disminuyó progresivamente desde la década de los ochenta hasta la del 2000. El grupo etario más afectados fue el de 36-60 años. Las localizaciones más frecuentemente afectadas fueron la planta y uñas de los pies. Conclusiones: Existe una disminución progresiva de la frecuencia de aislamiento de E. floccosum en el período estudiado. El sexo masculino y el grupo etario de 36-60 años fueron los más afectados. Las localizaciones más frecuentes fueron la planta y uñas de los pies.

Background: Dermatophytoses are frequent infections in human, which are produced by fungus genera Trichophyton, Microsporum and Epidermophyton. Aim: To determine frequency of E. floccosum in isolated dermatophyte in a laboratory from Valparaíso during the last three decades, in addition to knowing the most frequent localization, age and gender of patients affected by this agent. Method: All superficial culture reports, issued by the Universidad de Valparaíso's mycology laboratory in the last three decades, with E. floccosum, Microsporum spp and Trichophyton spp development, has been reviewed. Patients age, gender, location of the injury and culture report has been registered in an excel spreadsheet. Results: The total number of reports with dermatophyte development in the culture was 6,780. Only 26 cases show E. floccosum development, 73% of this (19/26) were present on men with and average age of 37 years. Frequency did progressively fall since eighty's until 2000 decade. The age group most affected by this etiological agent was 30-36 years. The most frequently localization in both man and woman were foot plant and nails. Conclusions: Frequency of isolation did decrease progressively in dermatophytose by E. floccosum for the study period. Masculine gender and 36-60 age group were the most affected. The most frequently localization were foot plant and nails.

Utilization of dynamic light scattering to evaluate Pterodon emarginatus oleoresin-based nanoemulsion formation by non-heating and solvent-free method

Abstract Pterodon emarginatus Vogel, Fabaceae, is a great source of bioactive compounds. The most known and studied herbal derivative from this species is an ambar-colored oleoresin that contains vouacapane diterpenes and volatile terpenoids, such as β-caryophyllene. Some recent papers aimed to generate nanoemulsions using this oleoresin for biological applications. However, they used high-energy methods that elevate costs of the process or heating procedures, which offer the disadvantage of possible volatile substances loss. Thus, as part of our ongoing studies with nanobiotechnology of natural products, especially regarding preparation of nanoemulsions with promising plant-based oils by low cost and low energy methods, we decided to evaluate the ability of non-heating and solvent-free method to generate P. emarginatus oleoresin-based nanoemulsions. Two non-ionic surfactants were used to generate the nanoemulsions by a simple homogenization method with vortex stirrer. Low mean droplet size (<180 nm) and low polydispersity index (<0.200) were observed even after one day of preparation. The low coefficient of variation for the analyzed parameters of different batches and similar profile for droplet size distribution suggested reproducibility of the method. After 30 days, some degree of droplet growth was observed on nanoemulsion prepared with polyethyleneglycol 400 monooleate, while almost no alteration was observed for nanoemulsion prepared with polysorbate 85. Programmed temperature ramp analysis revealed that no major effects on droplet size and polydispersity index were observed, suggesting the robustness of formed nanoemulsions. Thus, the present study shows for the first time the formation of sucupira-based nanoemulsions by a simple, low cost and ecofriendly method. This study opens new perspectives for bioactive evaluation of this novel nano-product.

Taxa de gravidez em mulheres submetidas à miomectomia histeroscópica / Pregnancy rate in women undergoing hysteroscopic myomectomy

Esta revisão tem como objetivo determinar o efeito da miomectomia histeroscópica sobre a performance reprodutiva de mulheres, com leiomiomas submucosos, tentando engravidar há, pelo menos, 12 meses e sem outras causas definidas de infertilidade. Foram revistos estudos clínicos controlados e randomizados (ECCR) publicados entre janeiro de 2005 e agosto de 2015 nas bases de dados MEDLINE (National Library of Medicine) e a Biblioteca Cochrane. Os desfechos examinados foram a taxa geral de gravidez, taxa de gravidez por tipo de leiomioma submucoso e tempo médio entre a intervenção e a gravidez. As publicações mostraram resultados favoráveis à realização da miomectomia histeroscópica quando comparada à não ressecção do leiomioma, atingindo taxas gerais de gravidez de até 63,4% no grupo intervenção e de apenas 28,2% no grupo controle. Resultados semelhantes ainda foram obtidos quando avaliadas as taxas de gravidez por tipo de leiomiomas submucosos. Apenas um estudo avaliou o tempo médio entre intervenção e gravidez, evidenciando redução significativa deste desfecho nas pacientes submetidas ao procedimento cirúrgico. Um importante benefício com a miomectomia histeroscópica não pode ser excluído nessas pacientes sugerindo um aumento nas taxas de gravidez quando essa cirurgia é realizada. Porém, mais ensaios clínicos controlados e randomizados são necessários para comprovar tal benefício.(AU)

This review aim to determine the effect of hysteroscopic myomectomy on reproductive performance of women with submucosal fibroids trying to conceive for at least 12 months and with otherwise unexplained infertility. The analysis was limited to only randomized controlled clinical trials (RCTs) published between January 2005 and August 2015, with reference to the MEDLINE database (National Library of Medicine) and the Cochrane Library. The selected endpoints were overall pregnancy rate, pregnancy rate by type of submucosal fibroids and mean time between intervention and pregnancy. The studies showed favorable results performing hysteroscopic myomectomy when compared to no resection of the fibroid, reaching overall pregnancy rates of up to 63,4% in the intervention group and only 28,2% in the control group. Similar results were also obtained when evaluated pregnancy rates by the type of submucosal fibroids. Only one study evaluated the mean time between intervention and pregnancy, showing significant reduction in this outcome in patients undergoing the surgical procedure. An important benefit with hysteroscopic myomectomy cannot be excluded in these patients, suggesting an increase in pregnancy rates when the surgery is performed. But more randomized controlled clinical trials are needed to confirm this benefit.(AU)